教育經曆：

2007.09-2012.06，安徽醫科大學，預防醫學專業，學士

2012.09-2015.06，北京大學，細胞生物學專業，碩士研究生

2015.09-2019.01，北京大學，免疫學，博士研究生

工作經曆：

2019.09-2021.09，北京大學，博士後

2021.12-現在，必威精装版app西汉姆联 ，副研究員

長期從事天然免疫相關研究。以昆蟲病原真菌為主要研究對象，以生物互作為主線，綜合運用多學科交叉研究手段，致力於探索病原微生物與宿主互作的分子機理，研發基於互作關係的害蟲防控新策略。

1.2024.01-2027.12，國家自然科學基金麵上項目（32370507），主持，在研；

2.2023.01-2028.12，國家重點研發計劃青年科學家項目（2022YFA0806900），子課題主持，在研；

3.2022.09-2025.12，國家重點研發計劃項目（2022YFD1400500）,子課題主持，在研；

4.2021.01-2023.12，國家自然科學基金青年科學基金項目（32000113），主持，已結題;

5.2021.01-2022.12，中國博士後科學基金第14批特別資助（2021T140026），主持，已結題。

1. Li J,Li JJ,Cao L,Chen Q,Ding D*,& Kang L*. An iron-binding protein of entomopathogenic fungus suppresses the proliferation of host symbiotic bacteria. Microbiome. 2024 Oct 15;12(1):202. doi: 10.1186/s40168-024-01928-4.
2. Cao L^# Luo Y^#,Guo X,Liu S,Li S,Li J,Zhang Z,Zhao Y,Zhang Q,Gao F,Ji X,Gao X,Li Y^*,You F^*. SAFA facilitates chromatin opening of immune genes through interacting with anti-viral host RNAs. PLOS Pathogens. 2022 Jun 3;18(6):e1010599.
3. Cao L^#,Liu S^#,Li Y,Yang G, Luo Y, Li S, Du H, Lin R, Wang P, You F^*. The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers. Cell Host & Microbe. 2019 Sep 11;26(3):369-384.e8.
4. Li S^#, Kuang M^#, Chen L, Li Y, Liu S, Du H, Cao L^*, You F^*. The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling. Cell Reports. 2021 Jan 19;34(3):108631.
5. Cao L^#, Yang G^#, Gao S, Jing C, Montgomery R, Yin Y, Wang P, Fikrig E, You F. HIPK2 is necessary for type I interferon–mediated antiviral immunity. Science Signaling. 2019. Mar 19;12(573).
6. Li Y^#, Xu J^#, Guo X^#, Li Z^#, Cao L, Liu S, Guo Y, Wang G, Luo Y, Zhang Z, Wei X, Zhao Y, Liu T, Wang X, Xia H, Kuang M, Guo Q, Li J, Chen L, Wang Y, Li Q, Wang F, Liu Q^*, You F^*. The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model. Genome Biology. 2023 Feb 1;24(1):20.
7. Chen J, Wei X, Wang X, Liu T, Zhao Y, Chen L, Luo Y, Du H, Li Y, Liu T, Cao L, Zhou Z, Zhang Z, Liang L, Li L, Yan X, Zhang X, Deng X, Yang G, Yin P, Hao J, Yin Z, You F. TBK1-METTL3 axis facilitates antiviral immunity. Cell Reports. 2022 Feb 15;38(7):110373.
8. Sun G, Qiu L, Yu L, An Y, Ding Y, Zhou L, Wu J, Yang X, Zhang Z, Tang X, Xia H, Cao L, You F, Zhao X, Du H. Loss of Function Mutation in ELF4 Causes Autoinflammatory and Immunodeficiency Disease in Human. Journal of Clinical Immunology. 2022 May;42(4):798-810.
9. Guo Q^#, Zhao Y^#, Li J^#, Liu J^#, Yang X^#, Guo X, Kuang M, Xia H, Zhang Z, Cao L, Luo Y, Bao L, Wang X, Wei X, Deng W, Wang N, Chen L, Chen J, Zhu H, Gao R, Qin C^#, Wang X^#, You F^#. Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19. Cell Host & Microbe. 2021 Feb 10;29(2):222-235.e4.
10. Li Y, Liu S, Cao L, Luo Y, Du H,Li S,Zhang Z, Guo X, Tian W, Wong C, You F. CBRPP: a new RNA-centric method to study RNA-protein interactions. RNA Biology. 2021 Feb 17;1-14.
11. Wang Y^#, Li S^#,Zhao Y, Zhang B, Li Y,Liu S, Du H,Cao L, Ou M,Ye X,Li P,Gao X, Wang P, Jing C, Shao F, Yang G, You F. The GRA15 protein from Toxoplasma gondii enhances host defense responses by activating the interferon stimulator STING. J Biol Chem. 2019 Nov 8;294(45):16494-16508.
12. Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. Plos One. 2016. 15;11(8).

(^#共同一作，^*通訊作者)