葉燕霞  博士 必威精装版app西汉姆联 副研究員。

工作經曆：

2024.02-至今，必威精装版app西汉姆联 ，副研究員

2016.01-2024.01，必威精装版app西汉姆联 ，助理研究員

2012.10-2016.01，中國醫學科學院北京協和醫院，風濕免疫科，博士後

主要致力於免疫、血液循環和心血管係統的衰老及相關疾病的研究，利用人幹細胞、靈長類動物模型、單細胞測序、多層次組學和基因編輯等技術係統解析衰老以及相關疾病的分子機製及幹預措施。以第一/共同第一作者在 Cell Stem Cell、Nature Aging（封麵論文）、Science Translational Medicine 等期刊發表研究論文，相關研究成果入選2023年度“中國生命科學十大進展”。

基金委，麵上基金項目，項目負責人。項目時間：2025.01-2028.12

科技部，國家重點研發計劃，課題骨幹。項目時間：2022.12-2027.11

科技部，國家重點研發計劃，課題骨幹。項目時間：2022.12-2025.12

基金委，青年科學基金項目，項目負責人。項目時間：2017.01-2019.12

1. Yanxia Ye^#, Honghao Zhang^#, Zijuan Xin^#, Wanling Sun^#, Lixiao Liu, Muzhao Xiong, Hongkai Zhao, Yiyuan Zhang, Jiaqi Geng, Liyun Zhao, Jingyi Li, Xiaoyu Jiang, Yuesheng Zuo, Shuai Ma, Hongjia Zhang, Si Wang, Guoguang Zhao, Juan Carlos Izpisua Belmonte, Jing Qu*, Weiqi Zhang*, Guang-Hui Liu*. Vitamin C attenuates primate bone marrow aging at the molecular and progenitor level. Cell Stem Cell. 2026. 33(8):1379-1397.
2. Yanxia Ye^#, Kuan Yang^#, Haisong Liu^#, Yang Yu^#, Moshi Song^#, Daoyuan Huang, Jinghui Lei, Yiyuan Zhang, Zunpeng Liu, Qun Chu, Yanling Fan, Sheng Zhang, Yaobin Jing, Concepcion Rodriguez Esteban, Si Wang, Juan Carlos Izpisua Belmonte, Jing Qu*, Weiqi Zhang*, Guang-Hui Liu*. SIRT2 counteracts primate cardiac aging via deacetylation of STAT3 that silences CDKN2B. Nature Aging. 2023. 3(10): 1269-1287. (Cover story)
3. Shuai Ma^#, Si Wang^#, Yanxia Ye^#, Jie Ren, Ruiqing Chen, Wei Li, Jiaming Li, Liyun Zhao, Qian Zhao, Guoqiang Sun, Ying Jing, Yuesheng Zuo, Muzhao Xiong, Yuanhan Yang, Qiaoran Wang, Jinghui Lei, Shuhui Sun, Xiao Long, Moshi Song, Shuyang Yu, Piu Chan, Jianwei Wang, Qi Zhou, Juan Carlos Izpisua Belmonte, Jing Qu*, Weiqi Zhang*, Guang-Hui Liu*. Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues. Cell Stem Cell. 2022. 29(6): 990-1005.e10.
4. Shuai Ma^#, Shuhui Sun^#, Lingling Geng^#, Moshi Song^#, Wei Wang, Yanxia Ye, Qianzhao Ji, Zhiran Zou, Si Wang, Xiaojuan He, Wei Li, Concepcion Rodriguez Esteban, Xiao Long, Guoji Guo, Piu Chan, Qi Zhou, Juan Carlos Izpisua Belmonte*, Weiqi Zhang*, Jing Qu*, Guang-Hui Liu*. Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Cell. 2020. 180(5): 984-1001.e22.
5. Shuyan Wang^#, Zhongfeng Liu^#, Yanxia Ye^#, Bingnan Li, Tiantian Liu, Weiqi Zhang, Guang-Hui Liu, Y. Alex Zhang, Jing Qu*, Dawei Xu*, Zhiguo Chen*. Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell Death & Disease. 2018. 9(9): 923.
6. Lidan Zhao, Yanxia Ye, Xuan Zhang*. B cells biology in systemic lupus erythematosus-from bench to bedside. Sci China Life Sci. 2015. 58(11): 1111-1125.
7. Xiangni Wu^#, Yanxia Ye^#, Jingwen Niu^#, Yang Li, Xin Li, Xin You, Hua Chen, Lidan Zhao, Xiaofeng Zeng, Fengchun Zhang, Fulin Tang, Wei He, Xuetao Cao, Xuan Zhang*, Peter E Lipsky*. Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus. Sci Transl Med. 2014. 6(246): 246ra99.
8. Yanxia Ye, Xiuyan Huang, Yaxing Zhang, Xinqiang Lai, Xiaoping Wu, Xiangfeng Zeng, Xiangao Tang, Yaoying Zeng*. Calcium influx blocked by SK&F 96365 modulates the LPS plus IFN-γ-induced inflammatory response in murine peritoneal macrophages. International Immunopharmacology. 2012. 12(2):384-393.
9. Yanxia Ye, Yaxing Zhang, Xiaoyu Lu, Xiuyan Huang, Xiangfeng Zeng, Xinqiang Lai, Yaoying Zeng*. The anti-inflammatory effect of the SOCC blocker SK&F 96365 on mouse lymphocytes after stimulation by Con A or PMA/ionomycin. Immunobiology. 2011. 216(9):1044-1053.